Computational screening
Sequence descriptors and recorded computational outputs help organise research candidates for further investigation. Prediction provenance is considered independently.
BiotaSift / Research
Discovery begins with evidence.
Explore the computational research framework behind BiotaSift: how we investigate peptide candidates, assess uncertainty and develop questions for experimental validation.
Our approach
From candidate to testable question.
Each step distinguishes a computational observation from an experimental conclusion.
Evidence review
Source documentation, reference comparisons and gaps are reviewed separately. Incomplete information is never treated as confirmation.
Experimental planning
Research candidates can be prioritised for laboratory testing. Antimicrobial activity and safety require experimental validation.
Evidence standards
Evidence, limitations and reproducibility.
The public research page describes our methods and standards. Candidate inventories, exact sequence-level results and sensitive scientific reports remain in restricted workspaces.
Computational research
Candidate records and analysis artifacts are versioned and reviewed with attention to reproducibility, data quality and provenance.
Sequence comparisons
Local reference searches help generate hypotheses. Short alignments are not presented as proof of functional homology or peptide novelty.
Biological activity
Antimicrobial efficacy, ecological effects, safety and mechanism of action are not established by computational screening alone.
Provenance and reproduction
Historical computational results and newly reproduced local analyses are distinguished. Missing original execution records are not treated as verified.
Research questions
What our results can—and cannot—show.
Are BiotaSift candidates experimentally validated?
The present research programme evaluates computational candidates. Biological activity, safety and suitability for particular applications must be experimentally tested.
Can a similar reference sequence identify an organism of origin?
No. An annotated reference organism describes that reference record, not the biological origin of the candidate.
Does computational screening demonstrate novelty?
No. Exploratory similarity searches alone do not establish novelty, patentability or freedom to operate.
Can research partners request access?
Yes. We welcome research enquiries. Access to candidate-level evidence, sequences and commercial terms is assessed through controlled partner processes.
Collaborate with BiotaSift
Build the next experiment.
Discuss computational evaluation, research partnerships and responsible biological validation. Candidate access and licensing are assessed individually.
Discuss a collaboration